Oxidative stress may be one of the most important and least understood phenomena in the human body. It affects all major systems, and plays a key role in accelerating heart disease and cancer risk. The very processes by which our bodies derive energy, through mitochondrial contribution of ATP energy, is impaired when excessive free radicals mutate mitochondrial cells. A measurement tool such as Revelar provides a new way to give patients a very specific method to prevent disease.
Dr. Dan Murphy, DC, Internationally Recognized Speaker
Why test for free radical damage?
Elevated levels of free radical damage — also known as oxidative stress — can contribute to a host of health problems. Free radical activity has been blamed for early aging, as well as tissue damage that can lead to chronic conditions such as arthritis, cancer, diabetes, strokes, Alzheimer's disease and other ailments.
How it works
Revelar measures the concentration of a set of aldehydes in a patient's breath. These aldehydes are byproducts of, and are directly correlated with, oxidative stress. The aldehydes measured are critical biomarkers of lipid peroxidation, the process by which excess free radicals attack lipids in cell membranes, causing tissue damage.
Reagent compounds in the breath tube react rapidly and completely with most of the saturated aldehydes associated with oxidative stress including hexanal, heptanal, decanal and MDA. This colorimetric reaction to cumulative aldehydes is then measured by the Revelar reflectance spectrophotometer, which generates a score based on the intensity of the reaction. Revelar's technology is capable of detecting parts per billion of aldehydes.
Because REVELAR measures the most important aldehydes produced by free radical damage, test results are more specific and accurate than any other available test.
As David Chernoff, MD, former Medical Director of Chiron Corporation, a leading developer of immuno-assays, says, "Revelar has been extensively shown to be an accurate and precise measurement of free radical damage in human breath condensate."
Lowering the level of aldehydes by reducing oxidative stress may improve health and slow the aging process. One way to do so is through the introduction of nutritional supplements and antioxidants. Antioxidants, stabilize free radicals and may protect cells from damage.
